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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC4 All Species: 23.33
Human Site: S309 Identified Species: 36.67
UniProt: Q9NPG8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NPG8 NP_001127859.1 344 39787 S309 P L V A W P P S A E P Q V H R
Chimpanzee Pan troglodytes XP_001142662 344 39946 S309 P L V A W P P S A E P Q V H R
Rhesus Macaque Macaca mulatta XP_001091630 344 39843 S309 P L V A W P P S A E P Q V H R
Dog Lupus familis XP_536886 343 39778 S309 R H V A R P L S A D T Q V N R
Cat Felis silvestris
Mouse Mus musculus Q9D6H5 343 39509 S309 P L V A W S P S A E P R I H Q
Rat Rattus norvegicus Q5FVR1 343 39379 S309 P L V A W S P S A E P Q I H Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506292 476 54090 L442 C Q T S E P R L E K P H V S R
Chicken Gallus gallus XP_414861 343 39066 C309 H H L T L Q P C D R Q V V Y K
Frog Xenopus laevis NP_001086024 326 37591 A297 K L K G R S L A A G S R K G Y
Zebra Danio Brachydanio rerio NP_956343 345 39869 R312 P Y S G H N C R T S Y N P F R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q8I0G4 403 46434 A370 Y S E Q S S S A S E K E I K S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002328533 299 33861 S276 M V F L V I V S L L L A G F F
Maize Zea mays NP_001150688 392 44335 S355 F M R S R T P S M E P V V R N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q3EBC2 397 44927 K357 S A R E E E V K A D A I A K R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RWM9 429 49597 V375 G E G E W E A V W R L K D V E
Conservation
Percent
Protein Identity: 100 98.2 94.1 77 N.A. 73.8 70.9 N.A. 45.1 50 45.6 45.5 N.A. N.A. N.A. 23 N.A.
Protein Similarity: 100 98.8 96.5 86.6 N.A. 85.1 83.1 N.A. 54.4 66.2 63.9 61.7 N.A. N.A. N.A. 35.9 N.A.
P-Site Identity: 100 100 100 53.3 N.A. 73.3 80 N.A. 26.6 13.3 13.3 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 66.6 N.A. 93.3 93.3 N.A. 40 33.3 26.6 13.3 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: 25.2 25.2 N.A. 23.9 N.A. 22.1
Protein Similarity: 39.8 42.6 N.A. 41.5 N.A. 38.4
P-Site Identity: 6.6 33.3 N.A. 13.3 N.A. 6.6
P-Site Similarity: 13.3 46.6 N.A. 20 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 40 0 0 7 14 54 0 7 7 7 0 0 % A
% Cys: 7 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 7 14 0 0 7 0 0 % D
% Glu: 0 7 7 14 14 14 0 0 7 47 0 7 0 0 7 % E
% Phe: 7 0 7 0 0 0 0 0 0 0 0 0 0 14 7 % F
% Gly: 7 0 7 14 0 0 0 0 0 7 0 0 7 7 0 % G
% His: 7 14 0 0 7 0 0 0 0 0 0 7 0 34 0 % H
% Ile: 0 0 0 0 0 7 0 0 0 0 0 7 20 0 0 % I
% Lys: 7 0 7 0 0 0 0 7 0 7 7 7 7 14 7 % K
% Leu: 0 40 7 7 7 0 14 7 7 7 14 0 0 0 0 % L
% Met: 7 7 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 0 0 0 0 7 0 7 7 % N
% Pro: 40 0 0 0 0 34 47 0 0 0 47 0 7 0 0 % P
% Gln: 0 7 0 7 0 7 0 0 0 0 7 34 0 0 14 % Q
% Arg: 7 0 14 0 20 0 7 7 0 14 0 14 0 7 47 % R
% Ser: 7 7 7 14 7 27 7 54 7 7 7 0 0 7 7 % S
% Thr: 0 0 7 7 0 7 0 0 7 0 7 0 0 0 0 % T
% Val: 0 7 40 0 7 0 14 7 0 0 0 14 47 7 0 % V
% Trp: 0 0 0 0 40 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 7 7 0 0 0 0 0 0 0 0 7 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _